Research
World-class Research
Filadelfia is a leader in epilepsy research at an international level.
REsearch
The primary goal is to help patients
The largest patient base is gathered at Filadelfia.
With 6,000 outpatient visits and 1,350 hospitalizations annually, Filadelfia’s research has a unique foundation for development and study. Filadelfia’s professors, researchers, and Ph.D. students focus on clinically applied research to benefit patients.
The researchers collaborate internationally to achieve the best treatment for patients and their relatives.
REsearch
Filadelfia’s Research Areas
Filadelfia conducts research in the diagnosis and treatment of epilepsy to better assist patients and their relatives.
Through research, we gain a greater understanding of the underlying disease mechanisms and issues for people with epilepsy, allowing us to improve treatment and contribute to the development of new targeted therapies. We combine clinical, genetic, and pharmacological approaches to closely address patient care and treatment.
Neurophysiological research is clinically oriented with the aim of diagnosing and thereby helping patients in their daily lives. We develop and validate mathematical algorithms for the precise localization of the sources of electrical signals in the brain that trigger epileptic seizures. This includes developing and validating mobile equipment that can automatically locate epileptic seizures. Neurophysiological research significantly contributes to clinical research in the implementation of artificial intelligence in epilepsy diagnostics.
Genetics and personalized medicine are major research areas where pediatricians, neurologists, neurophysiologists, geneticists, and basic researchers closely collaborate on genetic epilepsy. Today, approximately 600 genes have been identified that can cause epilepsy. By mapping a patient’s genes and potential genetic defects, medication and treatment can be tailored. The goals are:
- To identify new genes that can cause neurological and developmental diseases, including epilepsy
- To understand the molecular mechanisms underlying the diseases being studied by examining the consequences of genetic changes at the cellular level
- To understand the relationship between specific genetic defects and associated clinical symptoms
- To explore potential new and/or alternative treatment options based on the genetic knowledge we acquire.
Filadelfia Research
Research reports
We are proud of our research at Filadelfia, which is at an international level. Our extensive international collaboration greatly contributes to a high and intensive level of research. We publish in scientific journals and annually compile our publications in a research report.
Our Researchers
Testimonials
The collaboration with Professor Beniczky’s team focuses on improving the diagnosis of epilepsy. In the long term, we hope that our partnership will contribute to a paradigm shift in how we currently interpret EEGs, resulting in quantitative, robust, and reproducible tools.
Professor Birgit Frauscher, Duke University, USA
Our collaboration with Professor Beniczky’s team and the Danish Epilepsy Center in Dianalund has overall been the most fruitful of our careers, enabling the development and achievement of numerous joint innovative projects to benefit people with epilepsy.
Professor Philippe Ryvlin, Lausanne University Hospital, Schweiz
Research
Filadelfia Research
Filadelfia’s research is widely represented throughout the organization but is organized into four research areas: Neurophysiology, Genetics and Personalized Medicine, Multidisciplinary Research, and CTU. The head of Filadelfia Research is the Health Director, Mads Ravnborg.
The secretariat function is organized within Filadelfia Research, providing secretarial support to the Research Committee and Project Office, and coordinating Hjernebroen and Journal Club.
